Biomimetic phantom for cardiac diffusion MRI

Biomimetic phantom for cardiac diffusion MRI.

PURPOSE Diffusion magnetic resonance imaging (MRI) is increasingly used to characterize cardiac tissue microstructure, necessitating the use of physiologically relevant phantoms for methods development. Existing phantoms are generally simplistic and mostly simulate diffusion in the brain. Thus, there is a need for phantoms mimicking diffusion in cardiac tissue. MATERIALS AND METHODS A biomime...

Novel anisotropic MRI diffusion phantom

Diffusion MRI (DMRI) comprises a growing list of methods, and with that the need for a reliable and robust MRI phantom with which one can calibrate and validate them. In this study we developed a novel anisotropic diffusion MRI phantom and demonstrated its applicability by producing fractional anisotropy (FA) maps derived from DTI and average pore diameter maps using double Pulsed Field Gradien...

ANISOTROPIC PHANTOM FOR DIFFUSION WEIGHTED MRI APPLICATIONS Instruction Manual

Anisotropic phantom to calibrate high-q diffusion MRI methods.

A silicon oil-filled glass capillary array is proposed as an anisotropic diffusion MRI phantom. Together with a computational/theoretical pipeline these provide a gold standard for calibrating and validating high-q diffusion MRI experiments. The phantom was used to test high angular resolution diffusion imaging (HARDI) and double pulsed-field gradient (d-PFG) MRI acquisition schemes. MRI-based ...

Cardiac diffusion MRI without motion effects.

We present a method for diffusion tensor MRI in the beating heart that is insensitive to cardiac motion and strain. Using a stimulated echo pulse sequence with two electrocardiogram (ECG) triggers, diffusion-encoding bipolar gradient pulses are applied at identical phases in consecutive cardiac cycles. In this experiment, diffusion is encoded at a single phase in the cardiac cycle of less than ...